| Identification | Back Directory | [Name]
Broussonol E | [CAS]
363134-28-5 | [Synonyms]
Broussonol E
4H-1-Benzopyran-4-one, 2-[3,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-3,5,7-trihydroxy-6-(3-methyl-2-buten-1-yl)- | [Molecular Formula]
C25H26O7 | [MOL File]
363134-28-5.mol | [Molecular Weight]
438.47 |
| Hazard Information | Back Directory | [Uses]
Broussonol E is a diprenylated flavonol. Broussonol E can be isolated from the leaves of Broussonetia kazinoki. Unlike some dinonylated flavonol derivatives, Broussonol E has no cytotoxicity to human tumor cell lines (A549, HCT-8, KB)[1]. | [Definition]
ChEBI: Papyriflavonol A is a pentahydroxyflavone that is flavone substituted with hydroxy groups at positions 3, 5, 7, 3' and 4' and prenyl groups at positions 6 and 5'. Isolated from Broussonetia papyrifera, it exhibits inhibitory activity against phospholipase A2 and tyrosinase. It has a role as a metabolite, an EC 3.1.1.4 (phospholipase A2) inhibitor and an EC 1.14.18.1 (tyrosinase) inhibitor. It is a member of flavonols, a pentahydroxyflavone and a 3'-hydroxyflavonoid. | [References]
[1] Zhang PC, et al. Five new diprenylated flavonols from the leaves of Broussonetia kazinoki. J Nat Prod. 2001 Sep;64(9):1206-9. DOI:10.1021/np010283o |
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