| Identification | Back Directory | [Name]
Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-methyl-, (3S,8aS)- (9CI) | [CAS]
36357-32-1 | [Synonyms]
cyclo(Pro-Ala)
Cyclo(L-Ala-L-Pro)
Cyclo(alanylprolyl)
Cyclo(alanylproline)
cis-cyclo(?-Ala-?-Pro)
Cyclo-(L-alanine-L-proline)
L-Prolyl-L-alanine diketopiperazine
Cyclo(L-Ala-L-Pro)/Cyclo(alanylproline)
(3S,8aS)-hexahydro-3-methylpyrrolo[1,2-a]pyrazine-1,4-dione
Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-methyl-, (3S,8aS)- (9CI)
(3S,8aS)-Hexahydro-3-methylpyrrolo[1,2-a]pyrazine-1,4-dioneNumbers: 61949-27-7 | [Molecular Formula]
C8H12N2O2 | [MDL Number]
MFCD20526828 | [MOL File]
36357-32-1.mol | [Molecular Weight]
168.19 |
| Chemical Properties | Back Directory | [Melting point ]
178-181℃ (methanol ) | [Boiling point ]
426.2±34.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [pka]
13.27±0.40(Predicted) | [Sequence]
Cyclo(Ala-Pro) |
| Hazard Information | Back Directory | [Uses]
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2[1]. | [Definition]
ChEBI: Cis-Cyclo[L-Ala-L-Pro] is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid. | [References]
[1] Chen C, et al. Streptomyces nigra sp. nov. Is a Novel Actinobacterium Isolated From Mangrove Soil and Exerts a Potent Antitumor Activity in Vitro. Front Microbiol. 2018 Jul 18;9:1587. DOI:10.3389/fmicb.2018.01587 |
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