| Identification | Back Directory | [Name]
thymidine 5'-(tetrahydrogen triphosphate) | [CAS]
365-08-2 | [Synonyms]
5'-TTP
Deoxy-TTP
5-Methyl-dUTP
dTTP.Free Acid
2'-Deoxythymidine triposphate
Thymidine-5''-triphosphoric acid
thymidine 5'-(tetrahydrogen triphosphate)
thymidine 5'-(tetrahydrogen triphosphate) USP/EP/BP
[hydroxy-[hydroxy-[[3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-oxolan-2-yl]methoxy]phosphoryl]oxy-phosphoryl]oxyphosphonic acid | [EINECS(EC#)]
206-669-7 | [Molecular Formula]
C10H17N2O14P3 | [MDL Number]
MFCD05881427 | [MOL File]
365-08-2.mol | [Molecular Weight]
482.17 |
| Chemical Properties | Back Directory | [storage temp. ]
Sealed in dry,2-8°C | [density ]
1.922±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
0.80±0.50(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Deoxythymidine-5'-triphosphate-13C10 (dTTP-13C10) dilithium is 13C-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA. | [Definition]
ChEBI: DTTP is a thymidine phosphate having a triphosphate group at the 5'-position. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a pyrimidine 2'-deoxyribonucleoside 5'-triphosphate and a thymidine phosphate. It is a conjugate acid of a dTTP(3-). | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5(2):191-202. DOI:10.1111/j.1365-2362.1975.tb00446.x |
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