| Identification | Back Directory | [Name]
1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol | [CAS]
36507-48-9 | [Synonyms]
Penbutolol
rac Penbutolol
rac Penbutolol-d9
Penbutolol Solution, 100ppm
1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol
1-(2-Cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol
2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-
2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]- (9CI)
PenbutololQ: What is
Penbutolol Q: What is the CAS Number of
Penbutolol Q: What is the storage condition of
Penbutolol | [EINECS(EC#)]
253-074-3 | [Molecular Formula]
C18H29NO2 | [MDL Number]
MFCD00864578 | [MOL File]
36507-48-9.mol | [Molecular Weight]
291.428 |
| Chemical Properties | Back Directory | [Melting point ]
55-75°C | [Boiling point ]
438.2±40.0 °C(Predicted) | [density ]
1.030±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Acetone (Slightly), Chloroform (Slightly), Methanol | [form ]
Solid | [pka]
13.90±0.20(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
Labelled Penbutolol (P220500). A β-adrenoceptor antagonist. Antihypertensive. | [Enzyme inhibitor]
This non-selective antihypertensive b-blocker (FW = 291.43 g/mol; CAS 36507-48-9; IUPAC: (S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)- propan-2-ol), known variously as Levatol?, Levatolol?, Lobeta?, Paginol?, Hostabloc?, and Betapressin, binds to both b1- and b2-adrenergic receptors, thus exhibiting the sympathomimetic effects of a partial b-adrenergic agonist, while also acting as a serotonin (5-HT1A) receptor antagonist. By blocking b-adrenergic receptors and the sympathetic nervous system, penbutolol decreases heart rate and cardiac output, thereby lowering arterial blood pressure. | [IC 50]
Beta-1 adrenergic receptor |
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| Company Name: |
BOC Sciences
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16314854226 |
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www.bocsci.com |
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Energy Chemical
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