| Identification | Back Directory | [Name]
(6R,7S,8S)-5,6,7,8-Tetrahydro-8-(4-hydroxy-3-methoxyphenyl)-3-methoxy-6,7-dimethyl-2-naphthalenol | [CAS]
36531-08-5 | [Synonyms]
Guaiacin
(6R,7S,8S)-5,6,7,8-Tetrahydro-8-(4-hydroxy-3-methoxyphenyl)-3-methoxy-6,7-dimethyl-2-naphthalenol
2-Naphthalenol, 5,6,7,8-tetrahydro-8-(4-hydroxy-3-methoxyphenyl)-3-methoxy-6,7-dimethyl-, (6R,7S,8S)- | [Molecular Formula]
C20H24O4 | [MDL Number]
MFCD30724981 | [MOL File]
36531-08-5.mol | [Molecular Weight]
328.4 |
| Chemical Properties | Back Directory | [Boiling point ]
484.5±45.0 °C(Predicted) | [density ]
1.151±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.08±0.35(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation[1]. | [Definition]
ChEBI:(+)-guaiacin is a lignan. It has a role as a metabolite. | [References]
[1] Lee MK, et al. Stimulatory activity of lignans from Machilus thunbergii on osteoblast differentiation. Biol Pharm Bull. 2007 Apr;30(4):814-7. DOI:10.1248/bpb.30.814 |
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