| Identification | Back Directory | [Name]
CLD-1 | [CAS]
368874-13-9 | [Synonyms]
CLD-1
CLDN1
SEMP1
UNQ481/PRO944
Senescence-associated epithelial membrane protein
Anti-Claudin 1, C-Terminal antibody produced in rabbit
Anti-Claudin-1 (C-Terminal), antibody produced in rabbit, affinity isolated antibody
3-Cyano-2-dicyanomethylidene-4-{trans,trans,trans-[3-(2-(p-N,N-bis(2-tert-butyldimethylsiloxyethyl)aminophenyl)vinyl)cyclohex-2-enylidene]-1-propenyl}-5,5-dimethyl-2,5-dihydrofuran
Propanedinitrile, 2-[4-[(1E,3E)-3-[3-[(1E)-2-[4-[bis[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]amino]phenyl]ethenyl]-5,5-dimethyl-2-cyclohexen-1-ylidene]-1-propen-1-yl]-3-cyano-5,5-dimethyl-2(5H)-furanylidene]- | [Molecular Formula]
C45H64N4O3Si2 | [MDL Number]
MFCD06411338 | [MOL File]
368874-13-9.mol | [Molecular Weight]
765.19 |
| Hazard Information | Back Directory | [Uses]
Anti-Claudin-1 (C-terminal) antibody produced in rabbit has been used in:
- immunoblotting
- immunofluorescence
- immunohistochemistry
| [Biological Activity]
Claudin-1 directly interacts with tight junction (TJ) -associated peripheral membrane proteins zonula occludens (ZO) proteins -1/2/3. Defects in the gene encoding claudin-1 are the cause of an autosomal recessive syndrome named ichthyosis-sclerosing cholangitis neonatal (NISCH). Claudinsμ expression is altered in several human cancers. Claudin-1 is frequently up-regulated in colorectal carcinomas (CRCs)resulting in tumor differentiation and progression. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
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