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368874-34-4

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368874-34-4 Structure

368874-34-4 Structure
IdentificationBack Directory
[Name]

TC 14012
[CAS]

368874-34-4
[Synonyms]

TC 14012
SGDDHDBBOJNZKY-LNDHEDFZSA-N
L-Argininamide, L-arginyl-L-arginyl-3-(2-naphthalenyl)-L-alanyl-L-cysteinyl-L-tyrosyl-N5-(aminocarbonyl)-L-ornithyl-L-lysyl-N5-(aminocarbonyl)-D-ornithyl-L-prolyl-L-tyrosyl-L-arginyl-N5-(aminocarbonyl)-L-ornithyl-L-cysteinyl-, cyclic (4→13)-disulfide
[Molecular Formula]

C90H140N34O19S2
[MDL Number]

MFCD19690961
[MOL File]

368874-34-4.mol
[Molecular Weight]

2066.42
Chemical PropertiesBack Directory
[storage temp. ]

Store at -80°C
[solubility ]

Methanol (Slightly), Water (Slightly)
[form ]

Powder
[color ]

White to off-white
[Water Solubility ]

Soluble to 1 mg/ml in water
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Description]

CXCR4 antagonist and ACKR3 (CXCR7) agonist (EC50 = 350 nM for CXCR7).
[Uses]

TC 14012 is a CXCR4 antagonist and ACKR3 (CXCR7) agonist
[IC 50]

CXCR4: 19.3 nM (IC50, antagonist site); CXCR7: 350 nM (EC50, agonist site); HIV
[storage]

Store at -80°C
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