| Identification | Back Directory | [Name]
bacimethrin | [CAS]
3690-12-8 | [Synonyms]
NSC 66577
Bacimetrin
bacimethrin
Bacimethrine
4-Amino-2-methoxy-5-pyrimidylmethanol
4-Amino-2-methoxy-5-pyrimidinemethanol
4-Amino-2-methoxypyrimidine-5-methanol
5-Pyrimidinemethanol, 4-amino-2-methoxy-
(4-Amino-2-methoxypyrimidin-5-yl)methanol
4-Amino-5-(hydroxymethyl)-2-methoxypyrimidine | [Molecular Formula]
C6 H9 N3 O2 | [MOL File]
3690-12-8.mol | [Molecular Weight]
155.15 |
| Chemical Properties | Back Directory | [Melting point ]
174℃ (decomposition) (methanol ) | [Boiling point ]
278.95°C (rough estimate) | [density ]
1.3092 (rough estimate) | [refractive index ]
1.6500 (estimate) | [storage temp. ]
2-8°C(protect from light) | [pka]
13.04±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Bacimethrin (NSC 66577) is an antibacterial agent and is thiamin biosynthesis antagonist.Bacimethrin inhibits bacterial and yeast growth[1][2]. | [References]
[1] Natalia S Nemeria, et al. Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin. Biochemistry. 2016 Feb 23;55(7):1135-48. DOI:10.1021/acs.biochem.5b01300
[2] J L Zilles, et al. Action of the thiamine antagonist bacimethrin on thiamine biosynthesis. J Bacteriol. 2000 Oct;182(19):5606-10. DOI:10.1128/JB.182.19.5606-5610.2000 |
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