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37115-32-5

37115-32-5 Structure

37115-32-5 Structure
IdentificationBack Directory
[Name]

ADINAZOLAM
[CAS]

37115-32-5
[Synonyms]

U-41123
ADINAZOLAM
Adinazolamum
Adinazolam (CRM)
8-Chloro-N,N-dimethyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-1-methanamine
4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine-1-methanamine, 8-chloro-N,N-dimethyl-6-phenyl-
γ-Aminobutyric acid Receptor,sickness,antihistamine,GABA Receptor,inhibit,Adinazolam,U-41123,U 41123,Huntington,Gamma-aminobutyric acid Receptor,anti-motion,piperazine,U41123,Inhibitor
[Molecular Formula]

C19H18ClN5
[MDL Number]

MFCD00865341
[MOL File]

37115-32-5.mol
[Molecular Weight]

351.83
Chemical PropertiesBack Directory
[Melting point ]

171-172.5° (US 4250094); mp 165-166° (DE 2201210)
[Boiling point ]

527.0±60.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[storage temp. ]

-10 to -25°C
[form ]

Solid
[pka]

pKa 6.2 (D2O/DClor D2O/NaOD ) (Uncertain);5.8±0.1(D2O/DClor D2O/NaOD ) (Uncertain)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H370
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P260-P264-P270-P280-P303+P361+P353-P307+P311-P321-P370+P378-P403+P235-P405-P501
[RIDADR ]

3249
[HazardClass ]

6.1(b)
[PackingGroup ]

III
Hazard InformationBack Directory
[Uses]

Antidepressant; sedative-hypnotic.
[Definition]

ChEBI: A triazolo[4,3-a][1,4]benzodiazepine having a dimethylaminomethyl group at the 1-position, a phenyl group at the 6-position and a chloro substituent at the 8-position.
[in vivo]

Adinazolam (6 mg/kg) increases shuttlebox avoidance acquisition in male Sprague-Dawley rats[2].

Animal Model:Male Sprague-Dawley rats weighing 409±30 g[2]
Dosage:6 mg/kg
Administration:Administered i.p. in 2 mL/kg
Result:Increased avoidance acquisition in 195% as compared to control animals.
Tags:37115-32-5 Related Product Information
29975-16-4 28981-97-7

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