ChemicalBook--->CAS DataBase List--->371167-61-2

371167-61-2

371167-61-2 Structure

371167-61-2 Structure
IdentificationBack Directory
[Name]

Z-LEU-LEU-LEU-FMK
[CAS]

371167-61-2
[Synonyms]

Z-LLL-FMK
Z-LEU-LEU-LEU-FMK
CATHEPSIN L INHIBITOR
CATHEPSIN B INHIBITOR
Z-LEU-LEU-LEU-FLUOROMETHYL KETONE
[Molecular Formula]

C27H42FN3O5
[MDL Number]

MFCD03453603
[MOL File]

371167-61-2.mol
[Molecular Weight]

507.64
Chemical PropertiesBack Directory
[Boiling point ]

704.367±60.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.092±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[storage temp. ]

−20°C
[form ]

solid
[pka]

11.136±0.46(predicted)
[Sequence]

Z-Leu-Leu-Leu-FMK
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Cathepsin L is a lysosomal cysteine proteinase th at metabolizes collagens and elastins. The roles and activity of Cathepsin L can be studied with the aid of peptide inhibitors such as the pentapeptide amide RKLLW-NH2 (Arg-Lys-Leu-Leu-Trp-NH2).
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