ChemicalBook--->CAS DataBase List--->371215-02-0

371215-02-0

371215-02-0 Structure

371215-02-0 Structure
IdentificationBack Directory
[Name]

5-Chloro-2-oxo-benzooxazole-3-carboxylic acid phenyl ester
[CAS]

371215-02-0
[Synonyms]

5-Chloro-2-oxo-benzooxazole-3-carboxylic acid phenyl ester
3(2H)-Benzoxazolecarboxylic acid, 5-chloro-2-oxo-, phenyl ester
[Molecular Formula]

C14H8ClNO4
[MDL Number]

MFCD01565777
[MOL File]

371215-02-0.mol
[Molecular Weight]

289.67
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

BZX1 is a novel inhibitor of O-GlcNAc transferase (OGT) activity.
[Uses]

OGT-IN-1 (Compound 5) is a potent OGT inhibitor. OGT-IN-1 inhibits sOGT and ncOGT with IC50s of 27 and 10 μM, respectively[1].
[References]

[1] Gross BJ, et al. Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc. 2005 Oct 26;127(42):14588-9. DOI:10.1021/ja0555217
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