| Identification | Back Directory | [Name]
PIK-inhibitors | [CAS]
371934-59-7 | [Synonyms]
MDK34597
p110α-IN-1
INVIVO34597
PIK-inhibitors
P110Α-IN-1;MDK34597
MDK34597 PIK-inhibitors
MDK34597 (PI3K inhibitor)
PIK-inhibitors(p110α-IN-1)
MDK34597; MDK-34597; MDK 34597. PI3K INHIBITOR
3-[4-(MORPHOLIN-4-YL)PYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL]ANILINE
Benzenamine, 3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]- | [Molecular Formula]
C19H17N5O2 | [MDL Number]
MFCD30475673 | [MOL File]
371934-59-7.mol | [Molecular Weight]
347.37 |
| Chemical Properties | Back Directory | [density ]
1.383±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble | [form ]
A crystalline solid | [pka]
3.31±0.10(Predicted) | [color ]
Light yellow to light brown | [InChI]
InChI=1S/C19H17N5O2/c20-13-4-1-3-12(11-13)17-22-15-14-5-2-6-21-19(14)26-16(15)18(23-17)24-7-9-25-10-8-24/h1-6,11H,7-10,20H2 | [InChIKey]
RQPKSOWRJPRYCN-UHFFFAOYSA-N | [SMILES]
C1(N)=CC=CC(C2=NC(N3CCOCC3)=C3OC4=NC=CC=C4C3=N2)=C1 |
| Hazard Information | Back Directory | [Uses]
PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC50 of 6.85[1]. | [References]
[1] Li Y, et al. Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110alpha inhibitors. J Mol Model. 2010 Sep;16(9):1449-60. DOI:10.1007/s00894-010-0659-y |
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| Company Name: |
ChemeGen Gold
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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