| Identification | Back Directory | [Name]
4-chloro-N-[3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)quinoxalin-2-yl]benzenesulfonamide | [CAS]
372087-80-4 | [Synonyms]
DQBS
4-chloro-N-[3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)quinoxalin-2-yl]benzenesulfonamide
Benzenesulfonamide, 4-chloro-N-[3-[(2,3-dihydro-1,4-benzodioxin-6-yl)amino]-2-quinoxalinyl]- | [Molecular Formula]
C22H17ClN4O4S | [MOL File]
372087-80-4.mol | [Molecular Weight]
468.91 |
| Hazard Information | Back Directory | [Description]
DQBS is an antagonist of HIV-1 Nef function. | [Uses]
DQBS can bind to HIV-1 nef protein, and inhibits Nef-dependent HIV replication[1]. | [References]
[1] Trible RP, et al. Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen. Retrovirology. 2013 Nov 14;10:135. DOI:10.1186/1742-4690-10-135 |
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