| Hazard Information | Back Directory | [Description]
A 201A is a nucleoside antibiotic isolated from Streptomyces capreolus. | [Uses]
A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation[1][2]. | [References]
[1] Nie S, et al. Total synthesis of nucleoside antibiotic A201A. J Am Chem Soc. 2014 Mar 19;136(11):4157-60. DOI:10.1021/ja501460j
[2] Wang J, et al. Bioinspired Total Synthesis of Complex Nucleoside Antibiotics A201A, A201D and A201E. Angew Chem Int Ed Engl. 2023 Jan 16;62(3):e202213810. DOI:10.1002/anie.202213810 |
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