| Identification | Back Directory | [Name]
FLAVOKAWAINC | [CAS]
37308-75-1 | [Synonyms]
FLAVOKAWAINC
Flavokavin C
Flavokavain C
(E)-2',4-Dihydroxy-4',6'-dimethoxychalcone
4,2'-Dihydroxy-4',6'-dimethoxy-trans-chalcone
2',4-Dihydroxy-4',6'-dimethoxy-trans-chalcone
(E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)-, (2E)- | [Molecular Formula]
C17H16O5 | [MDL Number]
MFCD00016489 | [MOL File]
37308-75-1.mol | [Molecular Weight]
300.31 |
| Chemical Properties | Back Directory | [Melting point ]
179-182 °C | [Boiling point ]
556.0±50.0 °C(Predicted) | [density ]
1.279±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMSO: 12.5 mg/mL (41.62 mM) | [form ]
Solid | [pka]
6.91±0.40(Predicted) | [color ]
Light yellow to orange | [Major Application]
food and beverages | [InChI]
1S/C17H16O5/c1-21-13-9-15(20)17(16(10-13)22-2)14(19)8-5-11-3-6-12(18)7-4-11/h3-10,18,20H,1-2H3/b8-5+ | [InChIKey]
UXUFMIJZNYXWDX-VMPITWQZSA-N | [SMILES]
O(C)c1c(c(cc(c1)OC)O)C(=O)\C=C\c2ccc(cc2)O |
| Hazard Information | Back Directory | [Chemical Properties]
Pale yellow powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of Piper methysticum Forst. | [Uses]
Flavokawain C?is a?chalcone found in the kava plant. Studies showed that?Flavokawain C can inhibit cell cycle and promote apoptosis in HCT 116 cells. In addition, natural chalcones have been?implicated as lead compounds for developing dual inhibitors against?Histone deacetylase enzymes (HDACs) and NF-κB. Flavokawain C is a related compound Flavokawain A (F371020). | [Definition]
ChEBI: Flavokawain C is a member of chalcones. |
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Synchem OHG
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www.synchem.de |
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