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3734-80-3

3734-80-3 Structure

3734-80-3 Structure
IdentificationBack Directory
[Name]

o-Bis(2-chloroethyl)aminomethylphenylalanine hydrochloride
[CAS]

3734-80-3
[Synonyms]

o-Bis(2-chloroethyl)aminomethylphenylalanine hydrochloride
[Molecular Formula]

C14H20Cl2N2O2
[MOL File]

3734-80-3.mol
[Molecular Weight]

319.23
Chemical PropertiesBack Directory
[Boiling point ]

394.6±42.0 °C(Predicted)
[density ]

1.277±0.06 g/cm3(Predicted)
[pka]

2.16±0.10(Predicted)
Hazard InformationBack Directory
[Description]

Ocaphane is a strong antitumor agent used on a number of animal tumors such as Brown-Pearce carcinoma. In clinical trials, it was found to be effective in treating patients with malignant pleural effusion and cancer of the head and neck. However, it was fairly toxic to hemopoietic organs.
[Uses]

Ocaphane (free acid) is an antitumor agent that inhibits tumor growth in the Ehrlich tumor mouse model[1].
[References]

[1] Xu B, et al. Advances in cancer chemotherapeutic drug research in China[J]. Recent advances in cancer research and therapy, 2012: 287.
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