| Identification | Back Directory | [Name]
CEPHAELINE HYDROCHLORIDE | [CAS]
3738-70-3 | [Synonyms]
CEPHAELINE HYDROCHLORIDE
CEPHAELINE HYDROCHLORIDE USP/EP/BP | [Molecular Formula]
C28H40Cl2N2O4 | [MDL Number]
MFCD14702529 | [MOL File]
3738-70-3.mol | [Molecular Weight]
539.53 |
| Hazard Information | Back Directory | [Uses]
Cephaeline hydrochloride ((-)-Cephaeline hydrochloride) is a phenolic alkaloid in Indian Ipecac roots. Cephaeline hydrochloride exhibits potent inhibition of both Zika virus (ZIKV) and Ebola virus (EBOV) infections[1][2]. | [IC 50]
EBOV | [References]
[1] N.P.Sahu, et al. Determination of emetine and cephaeline in Ipecac roots by high- performance liquid chromatography. Journal of Chromatography A. 1982 Apr; 238( 2):525-529.
[2] Yang S, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discov. 2018 Jun 5;4:31. DOI:10.1038/s41421-018-0034-1 |
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