| Identification | Back Directory | [Name]
10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione | [CAS]
374543-46-1 | [Synonyms]
10-(4-methylphenyl)-7-phenyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione
5H-Indeno[1,2-b]quinoline-9,11-dione, 6,7,8,10-tetrahydro-10-(4-methylphenyl)-7-phenyl- | [Molecular Formula]
C29H23NO2 | [MOL File]
374543-46-1.mol | [Molecular Weight]
417.5 |
| Hazard Information | Back Directory | [Uses]
SARS-CoV-2-IN-100 (Compound 172) is an inhibitor of SARS-CoV-2, demonstrating broad-spectrum antiviral activity against various SARS-CoV-2 variants. SARS-CoV-2-IN-100 exhibits synergistic effects with Nirmatrelvir, which can reduce the risk of antiviral drug resistance[1]. | [References]
[1] Chan C C Y, et al. Identification of novel small-molecule inhibitors of SARS-CoV-2 by chemical genetics[J]. Acta Pharmaceutica Sinica B, 2024. DOI:10.1016/j.apsb.2024.05.026 |
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