| Identification | Back Directory | [Name]
2'-C-Methylguanosine | [CAS]
374750-30-8 | [Synonyms]
2-C′-MeG
-C-Methylguanosine
2'-C-Methylguanosine
2’-β-C-Methylguanosine
Guanosine, 2'-C-methyl-
2’-C-β-Methyl Guanosine
2'-C-beta-Methylguanosine
2'-C-Methylguanosine USP/EP/BP
2-AMino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)-1H-purin-6(9H)-one | [Molecular Formula]
C11H15N5O5 | [MDL Number]
MFCD13194756 | [MOL File]
374750-30-8.mol | [Molecular Weight]
297.27 |
| Chemical Properties | Back Directory | [Boiling point ]
733.1±70.0 °C(Predicted) | [density ]
2.03 | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
H2O: soluble5mg/mL, clear (warmed) | [form ]
powder | [pka]
13.31±0.70(Predicted) | [color ]
white to beige | [InChI]
1S/C11H15N5O5/c1-11(20)6(18)4(2-17)21-9(11)16-3-13-5-7(16)14-10(12)15-8(5)19/h3-4,6,9,17-18,20H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,9-,11-/m1/s1 | [InChIKey]
NVKAMPJSWMHVDK-GITKWUPZSA-N | [SMILES]
C[C@]1([C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O)O |
| Safety Data | Back Directory | [WGK Germany ]
3 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Uses]
2’-C-β-Methyl Guanosine is an anti-HCV agent. 2’-C-β-Methyl Guanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus. | [Uses]
2’C-β-Methyl Guanosine is an anti-HCV agent. 2’C-β-Methyl Guanosine is an intermediate in the synthesis of novel double prodrug INX-08189, a new clinical candidate for hepatitis C virus. | [Uses]
A nucleoside derivative as antiviral, antitumor, and antidiabetic prodrug agents |
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