| Identification | Back Directory | [Name]
ANTIPAIN HYDROCHLORIDE DIHYDRATE | [CAS]
37691-11-5 | [Synonyms]
Aids006469
Aids-006469
PHE-ARG-VAL-ARG-CHO
ANTIPAIN ~10000 U/MG
Phe-co-Arg-Val-L-Arg-h
Antipain research grade
ANTIPAIN HYDROCHLORIDE DIHYDRATE
ANTIPAIN HYDROCHLORIDE DIHYDRATE USP/EP/BP
4-((aminoiminomethyl)amino)-1-formylbutyl)-
Nα-[Nα-[[(1-Carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl]-N-(1-formyl-4-guanidinobutyl)-L-valinamide
N2-[[(1-carboxyphenethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-valinamide
N2-[[(1-Carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-valinamide
L-Valinamide, N2-[[(1-carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-
Nα-[N2-[[(1-Carboxy-2-phenylethyl)amino]carbonyl]-L-arginyl]-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-valinamide
L-Valinamide, N(sup 2)-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)- | [EINECS(EC#)]
253-631-0 | [Molecular Formula]
C27H44N10O6 | [MDL Number]
MFCD04119720 | [MOL File]
37691-11-5.mol | [Molecular Weight]
604.7 |
| Hazard Information | Back Directory | [Uses]
Antipain is a reversible inhibitor of Ser and Cys proteases. | [General Description]
Chemical structure: peptide | [Biochem/physiol Actions]
Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells. | [in vivo]
The intact, cycling female mice received subcutaneous injections of Antipain (3 mg) for 16 days, their uteri shows significant diminution in weight and total DNA when compared to untreated controls[4].
Antipain (100 μg/g body wt; i.p.; at 12h intervals from 0 to 120 h or 240 to 360 h) shows inhibitory effect on Urethane-induced lung neoplasia in mice[5]. |
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BOC Sciences
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Sigma-Aldrich
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Alabiotech Inc.
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001-619-354-5251 |
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www.alabiotech-e.com |
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