| Identification | Back Directory | [Name]
2,3-DIHYDRO-ISOXAZOLO[3,2B]QUINAZOLIN-9-ONE | [CAS]
37795-69-0 | [Synonyms]
W-2429
NSC294836
2,3-DIHYDRO-ISOXAZOLO[3,2B]QUINAZOLIN-9-ONE
2,3-Dihydro-9H-isoxazolo[3,2-b]quinazolin-9-one
9H-Isoxazolo[3,2-b]quinazolin-9-one, 2,3-dihydro- | [Molecular Formula]
C10H8N2O2 | [MDL Number]
MFCD00869447 | [MOL File]
37795-69-0.mol | [Molecular Weight]
188.18 |
| Chemical Properties | Back Directory | [Boiling point ]
323.18°C (rough estimate) | [density ]
1.2577 (rough estimate) | [refractive index ]
1.5910 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO |
| Hazard Information | Back Directory | [Uses]
W-2429 (NSC294836) is considerably more effective than acetylsalicylic acid in inhibiting carrageenan-induced edema and in reducing brewer's yeast-induced fever in rats[2]. | [in vivo]
W-2429 is a non-narcotic analgesic agent. Treatment with W-2429 is well tolerated by rats as well as dogs. In the dog, the only signs of toxicity observed are decreased appetite and salivation at 100 mg/kg/day W-2429. No other significant evidence of physical, chemical, gross or histopathologic change is observed[1]. | [storage]
Store at -20°C | [References]
[1] Banerjee BN, et al. Toxicological investigation of 2,3-dihydro-9H-isoxazolo[3,2-b]quinazolin-9-one (W-2429). Acuteand subacute toxicity in mice, rats and dogs. Arzneimittelforschung. 1977;27(4):793-801. PMID:301393
[2] Reisner DB, Ludwig BJ, Simon E, Dejneka T, Sofia RD. 2,3-Dihydro-9H-isoxazolo[3,2-b]quinazolin-9-ones and 3,4-dihydro-(1,2)-oxazino [3,2-b]quinazolin-10(2H)-ones. Arzneimittelforschung. 1977;27(4):766-770. PMID:301391 |
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|