Identification | Back Directory | [Name]
HUMAN IL-8 | [CAS]
378763-92-9 | [Synonyms]
IL-8 RHIL-8 HUMAN IL-8 HUMAN CXCL8 IL-8, HUMAN IL-8 (77AA), HUMAN IL-8 (72AA), HUMAN HUMAN INTERLEUKIN 8 IL-8 [HOMO SAPIENS] INTERLEUKIN 8 HUMAN REC MONOCYTE IL-8 (HUMAN) IL-8/72 AMINO ACIDS HUMAN INTERLEUKIN-8 (72AA), HUMAN INTERLEUKIN-8 (77AA), HUMAN REC ENDOTHELIAL IL-8 (HUMAN) Mouse Anti Human Interleukin-8 INTERLEUKIN-8, HUMAN, RECOMBINANT REC MONOCYTE INTERLEUKIN-8 (HUMAN) REC ENDOTHELIAL INTERLEUKIN-8 (HUMAN) INTERLEUKIN-8(MONOCYTE-DERIVED), HUMAN INTERLEUKIN-8, HUMAN, RECOMBINANT, E COLI INTERLEUKIN-8(ENDOTHELIAL CELL-DERIVED), HUMAN 2-Furancarboxylic acid, 5-[1-amino-8,9-dihydro-8,8-dimethyl-5-(4-morpholinyl)-6H-pyrano[4,3-d]thieno[2,3-b]pyridin-2-yl]- | [Molecular Formula]
C21H23N3O5S | [MDL Number]
MFCD00131404 | [MOL File]
378763-92-9.mol | [Molecular Weight]
429.49 |
Chemical Properties | Back Directory | [Boiling point ]
715.1±60.0 °C(Predicted) | [density ]
1.391±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [form ]
lyophilized powder | [pka]
2.60±0.10(Predicted) | [biological source]
human |
Hazard Information | Back Directory | [Uses]
Interleukin-8 (IL-8) human has ben used to:
- measure neutrophil chemotoxis
- study the uptake of apoptotic cells by meningothelial cells
- study the effect of IL-8 on expression and secretion of urocortin-1 by human umbilical vein endothelial cells
| [Biochem/physiol Actions]
Interleukin-8 (IL-8) was formerly called monocyte-derived neutrophil chemotactic factor. It belongs to the chemokine α or C-X-C family. Like other members of this family, the mature form of IL-8 has four cysteine residues and the first two cysteine residues are separated by glutamine. IL-8 shows chemotactic activity in vitro for T cells, neutrophils and basophils. Mutation in IL-8 can increase risk to acute pancreatitis. |
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