ChemicalBook--->CAS DataBase List--->3788-44-1

3788-44-1

3788-44-1 Structure

3788-44-1 Structure
IdentificationBack Directory
[Name]

H-TYR-HIS-OH
[CAS]

3788-44-1
[Synonyms]

YH
H-TYR-HIS-OH
L-Tyr-L-His-OH
L-Histidine, L-tyrosyl-
[Molecular Formula]

C15H18N4O4
[MDL Number]

MFCD00238237
[MOL File]

3788-44-1.mol
[Molecular Weight]

318.33
Chemical PropertiesBack Directory
[Melting point ]

270 °C
[Boiling point ]

763.4±60.0 °C(Predicted)
[density ]

1.421±0.06 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

2.83±0.10(Predicted)
[Sequence]

H-Tyr-His-OH
Hazard InformationBack Directory
[Uses]

Tyrosylhistidine is a dipeptide consisting of tyrosine and histidine (Tyr-His). Tyrosylhistidine is an orally active antihypertensive peptide. Tyrosylhistidine reduces blood pressure in mice in a model of spontaneous hypertension[1].
[Definition]

ChEBI: Tyr-His is a dipeptide formed from L-tyrosine and L-histidine residues. It has a role as a metabolite. It is functionally related to a L-tyrosine and a L-histidine.
[References]

[1] Suetsuna K, et al. Antihypertensive effects of Undaria pinnatifida (wakame) peptide on blood pressure in spontaneously hypertensive rats. J Nutr Biochem. 2004 May;15(5):267-72. DOI:10.1016/j.jnutbio.2003.11.004
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