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37924-13-3

37924-13-3 Structure

37924-13-3 Structure
IdentificationBack Directory
[Name]

PERFLUIDONE
[CAS]

37924-13-3
[Synonyms]

Destun
sb1528
mbr8251
MBR 8251
PERFLUIDONE
N-(4-Phenylsulfonyl-o-tolyl)trifluoromethanesulfonamide
2-Methyl-4-(Phenylsulfonyl)trifluoromethanesulfonanilide
1,1,1-Trifluoro-4'-(phenylsulfonyl)methanesulfono-o-toluidide
n-(4-phenylsulfonyl-o-tolyl)-1,1,1-trifluoro-methanesulfonamid
n-(4-phenylsulfonyl-o-tolyl)-1,1,1-trifluoromethanesulfonamide
1,1,1-trifluoro-n-(4-phenylsulphonyl-o-tolyl)methanesulphonamide
Methanesulfonamide, N-(4-phenylsulfonyl-o-tolyl)-1,1,1-trifluoro-
Trifluoro-N-[2-methyl-4-(phenylsulfonyl)phenyl]methanesulfonamide
1,1,1-Trifluoro-N-(2-methyl-4-(phenylsulfonyl)phenyl)methanesulfonamide
methanesulfonamide,1,1,1-trifluoro-N-[2-methyl-4-(phenylsulfonyl)phenyl]-
Methanesulfonamide, 1,1,1-trifluoro-N-[2-methyl-4-(phenylsulfonyl)phenyl]-
1,1,1-trifluoro-N-(4-phenylsulphonyl-o-tolyl)methanesulphonamide perfluidone
[EINECS(EC#)]

253-718-3
[Molecular Formula]

C14H12F3NO4S2
[MDL Number]

MFCD01632780
[MOL File]

37924-13-3.mol
[Molecular Weight]

379.37
Chemical PropertiesBack Directory
[Melting point ]

142-144°
[Boiling point ]

471.9±55.0 °C(Predicted)
[density ]

1.4504 (estimate)
[pka]

2.5(at 25℃)
[Water Solubility ]

60mg/L(22 ºC)
[Henry's Law Constant]

1.3×102 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
[EPA Substance Registry System]

Perfluidone (37924-13-3)
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-36
[Toxicity]

mouse,LD50,oral,920mg/kg (920mg/kg),Farm Chemicals Handbook. Vol. -, Pg. C233, 1991.
Hazard InformationBack Directory
[Uses]

Herbicide.
[Uses]

Perfluidone is a plant growth regulator and a herbicide.
[Definition]

ChEBI: Perfluidone is a sulfonamide.
[Production Methods]

The industrial synthesis of perfluidone is not described in open literature. However, it can be inferred from its chemical structure. Industrial manufacture would begin with preparation of the substituted aniline precursor, which is then sulfonylated using a phenylsulfonyl chloride or equivalent reagent to introduce the phenylsulfonyl group. In parallel, trifluoromethanesulfonyl chloride (or a related activated sulfonylating agent) is prepared to supply the trifluoromethanesulfonamide fragment. These two components are then coupled through amide forming sulfonylation, yielding the characteristic bis sulfonylated structure of perfluidone. After condensation, the crude product would be purified through solvent washing, filtration, and crystallisation to achieve technical grade purity.
[Mechanism of action]

Interferes with protein biosynthesis and with cellular respiration. Selective acting via contact and root absorption
[Pesticide Type]

Herbicide
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