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379247-14-0

379247-14-0 Structure

379247-14-0 Structure
IdentificationBack Directory
[Name]

8H-Phthalazino[1,2-b]quinazolin-8-one, 5-[[3-(dimethylamino)propyl]amino]-
[CAS]

379247-14-0
[Synonyms]

BMH7
BMH-7
BMH 7
8H-Phthalazino[1,2-b]quinazolin-8-one, 5-[[3-(dimethylamino)propyl]amino]-
[Molecular Formula]

C20H21N5O
[MOL File]

379247-14-0.mol
[Molecular Weight]

347.41
Chemical PropertiesBack Directory
[Boiling point ]

532.9±52.0 °C(Predicted)
[density ]

1.27±0.1 g/cm3(Predicted)
[pka]

9.43±0.28(Predicted)
Hazard InformationBack Directory
[Description]

BMH-7 is a p53 activator with potent antitumor activity. It regulates the p53 signaling pathway in bladder cancer cells. BMH-7 also induces apoptosis, changes cell size, and leads to cell death. BMH-7 is derived from quinazolinone, a small molecule that is able to activate the p53 tumor suppressor pathway.
[Uses]

Histamine H4 receptor antagonist-2 serves as a potent activator of p53, demonstrating significant antitumor efficacy.
Spectrum DetailBack Directory
[Spectrum Detail]

8H-Phthalazino[1,2-b]quinazolin-8-one, 5-[[3-(dimethylamino)propyl]amino]-(379247-14-0)1HNMR
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