ChemicalBook--->CAS DataBase List--->380192-76-7

380192-76-7

380192-76-7 Structure

380192-76-7 Structure
IdentificationBack Directory
[Name]

2(1H)-Isoquinolineethanol, α-[[(4-chlorophenyl)methoxy]methyl]-3,4-dihydro-
[CAS]

380192-76-7
[Synonyms]

WAY-380064-A
2(1H)-Isoquinolineethanol, α-[[(4-chlorophenyl)methoxy]methyl]-3,4-dihydro-
[Molecular Formula]

C19H22ClNO2
[MOL File]

380192-76-7.mol
[Molecular Weight]

331.84
Chemical PropertiesBack Directory
[Boiling point ]

497.4±45.0 °C(Predicted)
[density ]

1?+-.0.06 g/cm3(Predicted)
[pka]

13.85±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

PRMT5-IN-46 (compound 278) inhibits PRMT5 with IC50 of 1-10 μM. PRMT5 is a methyltransferase which is associated with specific genetic alterations. PRMT5-IN-46 can be used for research of proliferative diseases, metabolic disorders, and blood diseases[1].
[References]

[1] DUNCAN, et al. PRMT5 inhibitors and uses thereof. WO2014100695. World Intellectual Property Organization. 2014-06-26.
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