ChemicalBook--->CAS DataBase List--->380480-75-1

380480-75-1

380480-75-1 Structure

380480-75-1 Structure
IdentificationBack Directory
[Name]

ppTG20
[CAS]

380480-75-1
[Synonyms]

ppTG20
[Molecular Formula]

C115H198N36O22
[MOL File]

380480-75-1.mol
[Molecular Weight]

2437.04
Chemical PropertiesBack Directory
[density ]

1.36±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[Sequence]

Gly-Leu-Phe-Arg-Ala-Leu-Leu-Arg-Leu-Leu-Arg-Ser-Leu-Trp-Arg-Leu-Leu-Leu-Arg-Ala
Hazard InformationBack Directory
[Uses]

ppTG20 is an amphiphilic cell penetrating peptide (KALA) that can be used for gene transfection. ppTG20 can bind to DNA, destabilize membranes, and mediate DNA transfection[1][2].
[References]

[1] Ma J, et al. Cell-penetrating peptides mediated protein cross-membrane delivery and its use in bacterial vector vaccine. Fish Shellfish Immunol. 2014 Jul;39(1):8-16. DOI:10.1016/j.fsi.2014.04.003
[2] Wyman TB, et al. Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry. 1997 Mar 11;36(10):3008-17. DOI:10.1021/bi9618474
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