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382608-09-5

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382608-09-5 Structure

382608-09-5 Structure

Identification	Back Directory
[Name] 3-(2,5-Dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one
[CAS] 382608-09-5
[Synonyms] 3-(2,5-Dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one 1-Azaspiro[4.5]dec-3-en-2-one, 3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-
[Molecular Formula] C18H23NO3
[MOL File] 382608-09-5.mol
[Molecular Weight] 301.38

Chemical Properties	Back Directory
[Boiling point ] 521.4±50.0 °C(Predicted)
[density ] 1.20±0.1 g/cm3(Predicted)
[pka] 4.50±1.00(Predicted)

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[Uses] (Rac)-Spirotetramat-enol (Compound 8) is a ligand of acetyl-CoA carboxylase that can be used to synthesize PROTAC ADC degrader (HY-169008)[1].
[References] [1] Xu Q, et al. Acetyl-CoA Carboxylase Proteolysis-Targeting Chimeras: Conceptual Design and Application as Insecticides. J Agric Food Chem. 2024 Aug 28;72(34):18809-18815. DOI:10.1021/acs.jafc.4c02793

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Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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