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38452-29-8

38452-29-8 Structure

38452-29-8 Structure
IdentificationBack Directory
[Name]

Tolmesoxide
[CAS]

38452-29-8
[Synonyms]

Tolmesoxide
4,5-Dimethoxy-2-(methylsulfinyl)toluene
[Molecular Formula]

C10H14O3S
[MOL File]

38452-29-8.mol
[Molecular Weight]

214.28
Chemical PropertiesBack Directory
[Boiling point ]

364.0±42.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

Tolmesoxide (RX71107) is a peripheral vascular dilator with blood pressure lowering activity. Tolmesoxide has shown direct vasodilation in the human forearm arterial bed and dorsal hand vein. Tolmesoxide can dose-dependently increase blood flow in the forearm and produce dilation during contraction of the dorsal hand veins. Tolmesoxide can be used to study high blood pressure and angina[1].
[References]

[1] Collier J G, et al. Comparison of effects of tolmesoxide (RX71107), diazoxide, hydrallazine, prazosin, glyceryl trinitrate and sodium nitroprusside on forearm arteries and dorsal hand veins of man[J]. British journal of clinical pharmacology, 1978, 5(1): 35. DOI:10.1111/j.1365-2125.1978.tb01595.x
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