| Identification | Back Directory | [Name]
N-(4-nitrophenyl)-2-thiophen-2-ylacetamide | [CAS]
384857-54-9 | [Synonyms]
WAY-297407
WAY297407,WAY 297407
2-Thiopheneacetamide, N-(4-nitrophenyl)-
N-(4-nitrophenyl)-2-thiophen-2-ylacetamide | [Molecular Formula]
C12H10N2O3S | [MDL Number]
MFCD01604524 | [MOL File]
384857-54-9.mol | [Molecular Weight]
262.28 |
| Chemical Properties | Back Directory | [Melting point ]
125-127 °C | [Boiling point ]
517.5±40.0 °C(Predicted) | [density ]
1.421±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 52 mg/mL (198.26 mM);Ethanol: 13 mg/mL (49.57 mM) | [form ]
Solid | [pka]
13.05±0.70(Predicted) | [color ]
Off-white to gray | [Water Solubility ]
Water: Insoluble |
| Hazard Information | Back Directory | [Uses]
Antitubercular agent-30 is an antibacterial agent against Mycobacterium tuberculosis (MIC=50 μg/mL). Antitubercular agent-30 has little cytotoxic effect on murine macrophage cells (LD85=~100 μg/mL)[1]. | [storage]
Store at -20°C | [References]
[1] Silva Louren?o MC, et al. Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6895-8. DOI:10.1016/j.bmcl.2007.09.096 |
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