ChemicalBook--->CAS DataBase List--->387818-26-0

387818-26-0

387818-26-0 Structure

387818-26-0 Structure
IdentificationBack Directory
[Name]

Curcumin Glucuronide
[CAS]

387818-26-0
[Synonyms]

Curcumin Impurity 1
Curcumin Glucuronide
1,6-Heptadiene-3,5-dione, 1-[4-(β-D-glucopyranosyloxy)-3-methoxyphenyl]-7-(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-
[Molecular Formula]

C27H30O11
[MDL Number]

MFCD30537609
[MOL File]

387818-26-0.mol
[Molecular Weight]

530.53
Chemical PropertiesBack Directory
[Melting point ]

110-113 °C
[Boiling point ]

799.2±60.0 °C(Predicted)
[density ]

1.408±0.06 g/cm3(Predicted)
[pka]

8.07±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

Curcumin monoglucoside is a flavonoid derivative possessing antioxidant, anti-apoptotic, neuroprotective effects, and antibacterial activity. Curcumin monoglucoside can be used in research on Parkinson's disease.[1][2]
[in vivo]

Curcumin monoglucoside (500μM) exerts antioxidant effects in the ROT Drosophila model by increasing GSH levels and decreasing ROS[1].

[References]

[1] Pandareesh MD, et al. Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson's Disease. Neurochem Res. 2016 Nov;41(11):3113-3128. DOI:10.1007/s11064-016-2034-6
[2] Li L M, et al. Antimicrobial and molecular interaction studies on derivatives of curcumin against Streptococcus pneumoniae which caused pneumonia[J]. Electronic Journal of Biotechnology, 2016, 19: 8-14.
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