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389868-12-6

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389868-12-6 Structure

389868-12-6 Structure
IdentificationBack Directory
[Name]

AC-GLU-GLU-VAL-VAL-ALA-CYS-PNA
[CAS]

389868-12-6
[Synonyms]

AC-EEVVAC-PNA
5A/5B PEPTIDE (3)
AC-GLU-GLU-VAL-VAL-ALA-CYS-PNA
Hepatitis C Virus 5A/5B Peptide (3)
[Molecular Formula]

C34H50N8O13S
[MDL Number]

MFCD00672480
[MOL File]

389868-12-6.mol
[Molecular Weight]

810.87
Chemical PropertiesBack Directory
[Boiling point ]

1289.9±65.0 °C(Predicted)
[density ]

1.339±0.06 g/cm3(Predicted)
[storage temp. ]

-15°C
[pka]

4.43±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein[1].
[References]

[1] Ede NJ, et al. Solid phase synthesis of peptide aldehyde protease inhibitors. Probing the proteolytic sites of hepatitis C virus polyprotein. J Pept Sci. 2000 Jan;6(1):11-8. DOI:10.1002/(SICI)1099-1387(200001)6:1<11::AID-PSC229>3.0.CO;2-#
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