| Identification | Back Directory | [Name]
2-[4-[2-[[(2S)-2-hydroxy-3-(2-thiophen-2-ylphenoxy)propyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carbonitrile | [CAS]
391920-32-4 | [Synonyms]
LY488756
LY-488756
LY 488756
Lubabegron
3-Pyridinecarbonitrile, 2-[4-[2-[[(2S)-2-hydroxy-3-[2-(2-thienyl)phenoxy]propyl]amino]-2-methylpropyl]phenoxy]-
2-[4-[2-[[(2S)-2-hydroxy-3-(2-thiophen-2-ylphenoxy)propyl]amino]-2-methylpropyl]phenoxy]pyridine-3-carbonitrile | [Molecular Formula]
C29H29N3O3S | [MOL File]
391920-32-4.mol | [Molecular Weight]
499.62 |
| Hazard Information | Back Directory | [Uses]
Lubabegron is a potent modulator of β-adrenergic receptor (β -AR). Lubabegron demonstrates antagonistic behavior at the β1 and β?2 receptor subtypes and agonistic behavior at the β?3 receptor subtype in cattle. Lubabegron reduces NH3 gas emissions from an animal or its waste[1]. | [IC 50]
β adrenergic receptor | [References]
[1] Kube JC, et al. Effects of various doses of lubabegron on calculated ammonia gas emissions, growth performance, and carcass characteristics of beef cattle during the last 56 days of the feeding period [published correction appears in Transl Anim Sci. 2021 Nov 15;5(4):txab210]. Transl Anim Sci. 2021;5(3):txab137. DOI:10.1093/tas/txab137 |
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