ChemicalBook--->CAS DataBase List--->39543-79-8

39543-79-8

39543-79-8 Structure

39543-79-8 Structure
IdentificationBack Directory
[Name]

Befunolol hydrochloride
[CAS]

39543-79-8
[Synonyms]

Bentos
Bentox
Benfuran
Glauconex
Befunolol HCl
Befunolol hydrochloride
2-Acetyl-7-[2-hydroxy-3-(isopropylamino)propoxy]benzofuran hydrochloride
Ethanone, 1-[7-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-2-benzofuranyl]-, hydrochloride
[Molecular Formula]

C16H22ClNO4
[MDL Number]

MFCD00243083
[MOL File]

39543-79-8.mol
Chemical PropertiesBack Directory
[Melting point ]

163°
[form ]

Liquid eye medication
Hazard InformationBack Directory
[Description]

Befunolol hydrochloride is the newest of the 8-adrenergic blockers to be introduced for the treatment of glaucoma. It is reportedly devoid of intrinsic sympathomimetic activity, with lower membrane-stabilizing activity than propranolol.
[Originator]

Kalcen (Japan)
[Brand name]

BENTOX
[Safety Profile]

Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion andsubcutaneous routes. An experimental teratogen. Otherexperimental reproductive effects. When heated todecomposition it emits toxic fumes of NOx and HCl. Abeta-adrenergi
Safety DataBack Directory
[Toxicity]

LD50 oral in rabbit: 400mg/kg
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