| Identification | Back Directory | [Name]
N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE | [CAS]
39837-08-6 | [Synonyms]
N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE
N-(Tetrahydro-2-oxo-3-thienyl)butanamide
N-(2-thioxotetrahydrofuran-3-yl)hexanaMide
N-(2-oxotetrahydrothiophen-3-yl)butyraMide
Butanamide, N-(tetrahydro-2-oxo-3-thienyl)-
2-Butyramido-4-mercaptobutyric acid gamma-(thiolactone) | [Molecular Formula]
C8H13NO2S | [MDL Number]
MFCD01862916 | [MOL File]
39837-08-6.mol | [Molecular Weight]
187.26 |
| Hazard Information | Back Directory | [Uses]
N-Butyryl-DL-homocysteine thiolactone is an N-acyl homoserine lactone (AHL) analogue. AHLs are potent inhibitors of biofilm formation and virulence factors, and has been used for degrading microbial communities, reducing bacterial pathogenicity[1][2]. | [References]
[1] Khalilzadeh P, et al. Growth inhibition of adherent Pseudomonas aeruginosa by an N-butanoyl-L-homoserine lactone analog. Can J Microbiol. 2010 Apr;56(4):317-25. DOI:10.1139/w10-013
[2] Iyer R, et al. Synthetic analogs of bacterial quorum sensors: US, US20110053890[P]. 2011-03-03. |
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