| Identification | Back Directory | [Name]
20-Hydroxyganoderic acid G | [CAS]
400604-12-8 | [Synonyms]
20-Hydroxyganoderic acid G
Lanost-8-en-26-oic acid, 3,7,12,20-tetrahydroxy-11,15,23-trioxo-, (3β,7β,12β)- | [Molecular Formula]
C30H44O9 | [MDL Number]
MFCD32197428 | [MOL File]
400604-12-8.mol | [Molecular Weight]
548.67 |
| Hazard Information | Back Directory | [Uses]
20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the agent discovery of nerve inflammation diseases associated with microglia activated by LPS[1]. | [References]
[1] Jiao Y, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61. DOI:10.1016/j.bmcl.2016.06.023 |
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