| Identification | Back Directory | [Name]
Bis-Propargyl-PEG7 | [CAS]
400775-35-1 | [Synonyms]
CAS_400775-35-1
Bis-Propargyl-PEG7
4,7,10,13,16,19,22-Heptaoxapentacosa-1,24-diyne | [Molecular Formula]
C18H30O7 | [MDL Number]
MFCD10699797 | [MOL File]
400775-35-1.mol | [Molecular Weight]
358.43 |
| Chemical Properties | Back Directory | [Boiling point ]
421.9±40.0 °C(Predicted) | [density ]
1.061±0.06 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Solid-Liquid Mixture | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Bis-propargyl-PEG7 is a homobifunctional reagent with two propargyl groups that can be used to form triazole linkages with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The hydrophilic PEG units help improve the solubility of the molecule in aqueous environment. | [Uses]
Bis-propargyl-PEG6 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG6 can be used to synthesize the polymer linked multimers of guanosine-3', 5'-cyclic monophosphates[1]. Bis-propargyl-PEG6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] Hans-Gottfried Genieser, et al. New polymer linked multimers of guanosine-3', 5'-cyclic monophosphates. WO2018041942A1. |
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Henan Alfachem Co.,Ltd.
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