| Identification | Back Directory | [Name]
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid | [CAS]
402849-27-8 | [Synonyms]
Indometacin Impurity 14
Indomethacin Impurity F
Indapamide EP Impurity F
Indomethacin EP Impurity F
Indometacin EP Impurity F
Indometacin (Indomethacin) EP Impurity F
Indomethacin (Indometacin) EP Impurity F
Indomethacin Impurity 6(Indomethacin EP Impurity F)
Indometacin 1,2-Propylene Glycol Esters (Mixture of Isomers)
4-Chloro-N''-(4-chlorobenzoyl)-N-(4-methoxyphenyl)benzohydrazide
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid
Indomethacin impurity 5/Indomethacin EP Impurity F/2-(4-Chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide-4-chloro-benzoic acid | [Molecular Formula]
C21H16Cl2N2O3 | [MOL File]
402849-27-8.mol | [Molecular Weight]
415.27 |
| Chemical Properties | Back Directory | [Melting point ]
159-163°C | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Soncited) | [form ]
Solid | [color ]
White to Pale Beige |
| Hazard Information | Back Directory | [Uses]
4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid is an impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.
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