| Identification | Back Directory | [Name]
4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID | [CAS]
405-85-6 | [Synonyms]
TIMTEC-BB SBB010215
Safinamide Impurity E
Safinamide Impueity C
ASINEX-REAG BAS 13355063
Safinamide Metabolite NW 1689
Safinamide Benzoic Acid Impurity
4-[(3-FLUOROBENZYL)OXY]BENZOIC ACID
4-[(3-fluorophenyl)methoxy]benzoate
4-[(3-fluorophenyl)methoxy]benzoic acid
Benzoic acid, 4-[(3-fluorophenyl)methoxy]-
4-[(3-FLUOROBENZYL)OXY]BENZENECARBOXYLIC ACID | [Molecular Formula]
C14H11FO3 | [MDL Number]
MFCD05663826 | [MOL File]
405-85-6.mol | [Molecular Weight]
246.23 |
| Chemical Properties | Back Directory | [Melting point ]
194-196°C | [Boiling point ]
393.4±22.0 °C(Predicted) | [density ]
1.289±0.06 g/cm3(Predicted) | [solubility ]
Ethanol: Slightly soluble | [pka]
4.40±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
4-[(3-Fluorobenzyl)oxy]benzoic acid is a metabolite of Safinamide. Safinamide is a potent and selective MAO-B inhibitor, and is used as an add-on treatment to treat Parkinson’s disease. | [References]
[1] LIANGYU ZOU. Identification, Characterization, and Quantification of Impurities of Safinamide Mesilate: Process-Related Impurities and Degradation Products.[J]. Journal of AOAC International, 2017, 120 6: 1029-1037. DOI: 10.5740/jaoacint.16-0218 |
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