| Identification | Back Directory | [Name]
1(2H)-Isoquinolinone, 3-[(dimethylamino)methyl]-6-methoxy-2-methyl-4-phenyl-, hydrochloride (1:1) | [CAS]
405165-77-7 | [Synonyms]
ISQ1
ISQ-1
ISQ 1
ISQ1 HCl
ISQ-1 HCl
ISQ 1 HCl
1(2H)-Isoquinolinone, 3-[(dimethylamino)methyl]-6-methoxy-2-methyl-4-phenyl-, hydrochloride (1:1) | [Molecular Formula]
C20H23ClN2O2 | [MOL File]
405165-77-7.mol | [Molecular Weight]
358.87 |
| Hazard Information | Back Directory | [Description]
ISQ-1 HCl is an an isoquinolinone (IKur) blocker. ISQ-1 HCl has been investigated for treatment of atrial arrhythmia. | [Uses]
ISQ-1 hydrochloride is an isoquinolinone (IKur) blocker with potential atrial arrhythmic activity. ISQ-1 exhibits cardiac electrophysiological characteristics similar to another structurally distinct IKur blocker previously reported from our laboratory[1]. | [References]
[1] In vivo cardiac electrophysiologic and antiarrhythmic effects of an isoquinoline IKur blocker, ISQ-1, in rat, dog, and nonhuman primate DOI:10.1097/FJC.0b013e3180325b2a |
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