| Chemical Properties | Back Directory | [Boiling point ]
495.8±40.0 °C(Predicted) | [density ]
1.438±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
7.62±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
JANEX-1-M is a metabolite of JANEX-1 (HY-15508). JANEX-1 is a JAK3 specific inhibitor, which can effectively inhibit mast cell degranulation and the release of pro-inflammatory mediators[1]. | [References]
[1] Uckun FM, et al. CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation. Drug Metab Dispos. 2002 Jan;30(1):74-85. DOI:10.1124/dmd.30.1.74 |
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TargetMol
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400-821-0310 15002144251 |
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www.targetmol.cn/ |
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