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40725-89-1

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40725-89-1 Structure

40725-89-1 Structure
IdentificationBack Directory
[Name]

3'-Deoxytubercidin
[CAS]

40725-89-1
[Synonyms]

NSC 124154
3'-Deoxytubercidin
3’-Deoxy-7-deazaadenosine
7-Deaza-3'-deoxyadenosine
3’-Deoxytubercidin, 3’-Deoxy-7-deazaadenosine
7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-(3-deoxy-β-D-erythro-pentofuranosyl)-
7-(3-Deoxy-beta-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
[Molecular Formula]

C11H14N4O3
[MOL File]

40725-89-1.mol
[Molecular Weight]

250.26
Chemical PropertiesBack Directory
[Boiling point ]

601.3±55.0 °C(Predicted)
[density ]

1.75±0.1 g/cm3(Predicted)
[pka]

12.97±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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