| Identification | Back Directory | [Name]
2(1H)-Quinolinone,3-hydroxy-6-methyl-(9CI) | [CAS]
408335-66-0 | [Synonyms]
3-hydroxy-6-Methylquinolin-2(1H)-one
2(1H)-Quinolinone, 3-hydroxy-6-methyl-
2(1H)-Quinolinone,3-hydroxy-6-methyl-(9CI) | [Molecular Formula]
C10H9NO2 | [MDL Number]
MFCD19704157 | [MOL File]
408335-66-0.mol | [Molecular Weight]
175.18 |
| Chemical Properties | Back Directory | [Melting point ]
228-229 °C(Solv: water (7732-18-5); methanol, 20% (67-56-1)) | [Boiling point ]
420.3±45.0 °C(Predicted) | [density ]
1.313±0.06 g/cm3(Predicted) | [pka]
8.68±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Tyrosinase-IN-29 (compound 5c) is a potent inhibitor of tyrosinase abTYR (IC50: 6.11 μM). Tyrosinase-IN-29 can be used to further study the inhibition of skin hyperpigmentation[1]. | [References]
[1] Jacobs ME, Petzer JP, Pretorius J, Cloete SJ, Crous C, Petzer A. Synthesis and evaluation of 3-hydroxyquinolin-2(1H)-one derivatives as inhibitors of tyrosinase. Bioorg Med Chem Lett. 2024 May 31;109:129823. |
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| Company Name: |
BePharm Ltd
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| Tel: |
400-685-9117 |
| Website: |
www.bepharm.com |
| Company Name: |
CHEMSTEP
|
| Tel: |
33 (0) 556 405 186 |
| Website: |
www.chemstep.com |
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