| Identification | Back Directory | [Name]
6-Chloro-2,3-diaminopyridine | [CAS]
40851-95-4 | [Synonyms]
6-Chloropyridine-2,3-diamin
6-Chloro-2,3-diaminopyridine
6-chloro-2,3-PyridinediaMine
2,3-PyridinediaMine, 6-chloro-
6-chloro-pyridine-2,3-diyldiamine
2,3-Diamino-6-chloropyridine ,97%
6-Chloro-2,3-diaminopyridine ISO 9001：2015 REACH
2,3-Diamino-6-chloropyridine | [EINECS(EC#)]
214-589-6 | [Molecular Formula]
C5H6ClN3 | [MDL Number]
MFCD00209966
| [MOL File]
40851-95-4.mol | [Molecular Weight]
143.57 |
| Chemical Properties | Back Directory | [Melting point ]
132.0 to 136.0 °C | [Boiling point ]
360.2±37.0 °C(Predicted) | [density ]
1.447±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
powder to crystal | [pka]
2.69±0.50(Predicted) | [color ]
White to Brown to Dark purple |
| Hazard Information | Back Directory | [Chemical Properties]
Dark green solid | [Synthesis]
6-Chloro-2-nitropyridin-3-amine (E-23) (8.8 g, 51 mmol, 1.0 eq.) was used as a raw material and mixed with Ruanne nickel (0.88 g) in methanol (100 mL). The reaction mixture was stirred at room temperature for 24 hours under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under vacuum to afford the target product 6-chloropyridine-2,3-diamine (E-24) (7 g, 95.6% yield) as a pale white solid. The product was detected by ESI-MS, m/z: 144.05 [M + H]+. | [References]
[1] Patent: WO2011/149937, 2011, A1. Location in patent: Page/Page column 40; 41; 84
[2] Patent: WO2013/78441, 2013, A1. Location in patent: Paragraph 00143; 00326
[3] Patent: WO2014/151147, 2014, A1. Location in patent: Paragraph 00641
[4] Patent: US2015/30588, 2015, A1. Location in patent: Page/Page column 66
[5] Patent: US9295673, 2016, B2. Location in patent: Page/Page column 341; 342 |
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