ChemicalBook--->CAS DataBase List--->4111-08-4

4111-08-4

4111-08-4 Structure

4111-08-4 Structure
IdentificationBack Directory
[Name]

2-hydroxy-2-methylbutanenitrile
[CAS]

4111-08-4
[Synonyms]

NSC 44232
2-hydroxy-2-methylbutanenitrile
Methyl ethyl ketone cyanohydrin
2-Methyl-2-hydroxybutyronitrile
[EINECS(EC#)]

223-892-5
[Molecular Formula]

C5H9NO
[MDL Number]

MFCD00042978
[MOL File]

4111-08-4.mol
[Molecular Weight]

99.13
Chemical PropertiesBack Directory
[Boiling point ]

90°C/10mmHg
[density ]

0.9303 g/cm3(Temp: 19 °C)
[storage temp. ]

Refrigerator
[solubility ]

soluble in Chloroform, Methanol
[form ]

Oil
[pka]

11.45±0.29(Predicted)
[color ]

Colourless
[EPA Substance Registry System]

Butanenitrile, 2-hydroxy-2-methyl- (4111-08-4)
Safety DataBack Directory
[TSCA ]

TSCA listed
[REACH Registrations]

Active
Hazard InformationBack Directory
[Chemical Properties]

Colourless Oil
[Definition]

ChEBI: A cyanohydrin in which the substituents on the alpha carbon are ethyl and methyl.
[Synthesis]

The primary method for synthesizing 2-hydroxy-2-methylbutanenitrile is the cyanohydrin reaction, which involves the nucleophilic addition of a cyanide anion to the carbonyl carbon of 2-butanone.
This reaction involves the addition of hydrogen cyanide (HCN) across the carbon-oxygen double bond of 2-butanone. Due to the extreme toxicity of HCN gas, it is commonly generated in situ by reacting a cyanide salt, such as sodium cyanide (NaCN) or potassium.
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