| Identification | Back Directory | [Name]
Apramycin sulfate | [CAS]
41194-16-5 | [Synonyms]
NEBRAMYCIN II
Apramycin sulfate
APRAMYCIN SULPHATE
NEBRAMYCIN II SULFATE
NEBRAMYCIN 11 SULPHATE
ApramycinSulphateCp2003
Apramycin Sulphate Soluble
Apramycin sulfate USP/EP/BP
Apramycin Sulphate Soluble Powder
Manufactuer CAS 41194-16-5 Apramycin Sulfate 99% Purity
5-AMINO-2-[[9-AMINO-8-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXOXY)-5-HYDROXY-4-METHYLAMINO-2,7-DIOXABICYCLO[4.4.0]DEC-3-YL]OXY]-6-(HYDROXYMETHYL)OXANE-3,4-DIOL
5-Amino-2-[[9-amino-8-(4,6-diamino-2,3-dihydroxy-cyclohexoxy)-5-hydroxy-4-methylamino-2,7-dioxabicyclo[4.4.0]dec-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4-diol sulfate | [EINECS(EC#)]
687-974-6 | [Molecular Formula]
C21H43N5O15S | [MDL Number]
MFCD06200257 | [MOL File]
41194-16-5.mol | [Molecular Weight]
637.66 |
| Hazard Information | Back Directory | [Description]
Apramycin was found in the culture broth of Streptomyces tenebrarius by Eli Lilly in 1967 as one of the eight components of the nebramycin complex. Apramycin is used in feed additives. | [Chemical Properties]
A yellow or yellow-brown powder, hygroscopic and easily soluble in water. Apramycin sulfate is an excellent drug for the prevention and treatment of bacterial diarrhea. | [Uses]
Apramycin sulfate has strong antibacterial activity against gram-negative bacteria and some gram-positive bacteria that are susceptible to infection in livestock and poultry, and can effectively prevent diarrhea caused by bacterial infection in livestock and poultry such as pigs, cattle and chickens , dysentery, dysplasia, etc.. | [Definition]
ChEBI: Apramycin sulfate is a glycoside and an amino cyclitol. | [Mechanism of action]
Aapramycin sulfate can interfere with the synthesis of prokaryotic riboprotein to inhibit harmful bacteria in animals. It is an aminocycloalcohol antibiotic, which has strong antibacterial activity against Gram-negative bacteria and some Gram-positive bacteria that are susceptible to infection in livestock and poultry, especially Escherichia coli and Salmonella that are resistant to other antibiotics Other pathogenic bacteria have quite strong antibacterial effect, and it is not easy to develop drug resistance. |
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