| Identification | Back Directory | [Name]
euonine | [CAS]
41758-69-4 | [Synonyms]
Evonimine
8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,14,22,23-pentakis(acetyloxy)-12-[(acetyloxy)methyl]-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, (8R,9R,10R,11S,12R,13R,14R,15S,18S,21S,22S)- | [Molecular Formula]
C38H47NO18 | [MDL Number]
MFCD21363953 | [MOL File]
41758-69-4.mol | [Molecular Weight]
805.78 |
| Chemical Properties | Back Directory | [Melting point ]
148-153 °C | [Boiling point ]
809.4±65.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
11.77±0.70(Predicted) |
| Hazard Information | Back Directory | [Description]
An amorphous alkaloid, isolated from Euonymus sieboldiana Blume, this base
is a white powder having no definite melting point. It occurs mainly in the
extract from the seeds and is dextrorotatory having a specific rotation of
[α]D + 21° (c 1.5, CHC13). | [Uses]
Evonimine (Euonine) is an alkaloid isolated from Tripterygium wilfordii Hook. Evonimine exhibits significant inhibition of humoral-mediated immunity using the haemolytic response as an indicator, and shows good anti-feeding activity against the lepidopteran Spodoptera littoralis[1]. | [Definition]
ChEBI: A sesquiterpene alkaloid that is isolated from Tripterygium wilfordii and exhibits immunosuppressive and insecticidal properties. | [References]
Sigiura, Yamada, Hirata, Tetrahedron Lett., 113 (1973) |
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