41927-89-3

Directory

41927-89-3 Structure

Identification	Back Directory
[Name] FOLINIC ACID CALCIUM SALT PENTAHYDRATE
[CAS] 41927-89-3
[Synonyms] LEUCOVORIN PENTAHYDRATE CALCIUM FOLINATE PENTAHYDRATE LEUCOVORIN CALCIUM SALT PENTAHYDRATE FOLINIC ACID CALCIUM SALT PENTAHYDRATE 5-HCO-H4PTEGLU CALCIUM SALT PENTAHYDRATE CITROVORUM FACTOR CALCIUM SALT PENTAHYDRATE FOLINIC ACID CALCIUM SALT PENTAHYDRATE USP/EP/BP 5-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID CALCIUM SALT 5-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID CALCIUM SALT PENTAHYDRATE 5-FORMYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID CALCIUM SALT PENTAHYDRATE N5-FORMYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID CALCIUM SALT PENTAHYDRATE
[Molecular Formula] C20H31CaN7O12
[MDL Number] MFCD00149465
[MOL File] 41927-89-3.mol
[Molecular Weight] 601.58

Chemical Properties	Back Directory
[Melting point ] 240-250 °C
[storage temp. ] 0-6°C
[solubility ] Aqueous (Slightly, Sonicated), Water (Sparingly, Heated, Sonicated)
[form ] Solid
[color ] Off-White to Pale Yellow
[Stability:] Hygroscopic

Safety Data	Back Directory
[Safety Statements ] 24/25

Hazard Information	Back Directory
[Uses] Anti-anemic (folate deficiency); antidote (to folic acid antagonists).
[Brand name] Wellcovorin (GlaxoSmithKline).
[Clinical Use] Folinic acid rescue Enhancement of 5-fluorouracil cytotoxicity in advanced colorectal cancer Folate deficiency
[Drug interactions] Potentially hazardous interactions with other drugs Should not be administered simultaneously with a folic acid antagonist as this may nullify the effect of the antagonist. Cytotoxics: avoid with panitumumab and raltitrexed.
[Metabolism] Folinic acid is a racemate where the L-form (L-5- formyl-tetrahydrofolate, L-5-formyl-THF), is the active enantiomer. The major metabolic product of folinic acid is 5-methyl-tetrahydrofolic acid (5-methyl-THF) which is predominantly produced in the liver and intestinal mucosa. 80-90% with the urine (5- and 10-formyltetrahydrofolates inactive metabolites), 5-8% with the faeces.

41927-89-3 suppliers list

Company Name:	Dideu Industries Group Limited
Tel:	+86-29-89586680 +86-15129568250 , +86-15129568250
Website:	https://www.dideu.com

Company Name:	XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
Tel:	+8618950047208 , +8618950047208
Website:	www.amitychem.com

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	821-50328103-801 18930552037
Website:	www.chemicalbook.com/ShowSupplierProductsList13285/0_EN.htm

Company Name:	Biosynth Biological Technology (Suzhou) Co Ltd
Tel:	51288865780
Website:	www.biosynth.com

Company Name:	Santa Cruz Biotechnology Inc
Tel:	021-60936350
Website:	www.scbt.com

Company Name:	Shanghai Sige Biological Technology Co., Ltd.
Tel:	021-57810052
Website:	www.chemicalbook.com/ShowSupplierProductsList166898/0_EN.htm

Company Name:	Shanghai Hao Test Biotechnology Co., Ltd.
Tel:	021-60443211 13585831301
Website:	www.ctesting-bio.com

Company Name:	Beijing Taize Ruida Technology Co., Ltd.
Tel:	400-800-8151 13651185998
Website:	www.chemicalbook.com/ShowSupplierProductsList112482/0_EN.htm

Company Name:	Nanjing Sai Ruirui Biotechnology Co., Ltd.
Tel:	025-87139386
Website:	www.shrbio.com

Company Name:	Beijing Huaxia Ocean Technology Co., Ltd.
Tel:	010-62898668 15311620006
Website:	www.hxbio.net

Tags:41927-89-3 Related Product Information

58-05-9 4271-30-1 56-06-4 6094-36-6 1492-18-8

HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

Login