| Identification | Back Directory | [Name]
8-CHLORO-CAMP | [CAS]
41941-56-4 | [Synonyms]
CN1256
CN 1256
ICN-1256
nsc614491
8-CL-CAMP
Ccris 846
Ncs 614491
Tocladesine
8-CHLORO-CAMP
8-chlorocyclicamp
8-Chloroadenosine3&rsquo
8-chloro-cyclicadenosinemonophosphate
8-Chloroadenosine 3′,5′-monophosphate
8-Chloroadenosine 3',5'-phosphoric acid
8-chloroadenosine,3’,5’-cyclicphosphate
8-Chloroadenosine-3',5'-O-monophosphate
8-Chloro cyclic adenosine 3',5'-phosphate
8-CHLOROADENOSINE-CYCLIC-3',5'-MONOPHOSPHATE
8-CHLOROADENOSINE 3',5'-CYCLIC-MONOPHOSPHATE
8-chloroadenosinecyclic3’,5’-(hydrogenphosphate)
adenosine,8-chloro-,cyclic3’,5’-(hydrogenphosphate)
8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate
8-Chloroadenosine-cyclic-3',5'-monophosphate dihydrate
8-Chloroadenosine 3',5'-Cyclicmonophate Sodium Salt
4h-furo(3,2-d)-1,3,2-dioxaphosphorin,adenosinederivatives
8-Chloroadenosine-3'',5''-cyclic monophosphoric acid sodium salt
8-chloroadenosine-3’,5’-cyclicmonophosphate(8-cl-camp),sodiumsalt
8-Chloro-cAMP, 8-Chloroadenosine 3μ,5μ-monophosphate, 8-Cl-cAMP | [Molecular Formula]
C10H11ClN5O6P | [MDL Number]
MFCD00153938 | [MOL File]
41941-56-4.mol | [Molecular Weight]
363.65 |
| Chemical Properties | Back Directory | [Boiling point ]
731.7±70.0 °C(Predicted) | [density ]
2.55±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
aqueous base: soluble | [form ]
White to off-white powder. | [pka]
0.95±0.60(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
8-Chloroadenosine 3'',5''-Cyclic Monophosphate is a cAMP analog with high selectivity for PKA I. Used in anti-cancer treatments. | [Biological Activity]
Membrane-permeable cAMP analog; resistant to hydrolysis by phosphodiesterases. | [in vivo]
In rat bearing balloon injury, 8-Chloro-cAMP (12 mg/kg) reduces, in a dose-dependent manner, neointimal area and neointima/media ratio after balloon injury. 8-Chloro-cAMP shows a reduction of proliferative activity of VSMCs in vivo[1]. | [storage]
Store at -20°C |
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