| Identification | Back Directory | [Name]
TLCK | [CAS]
4238-41-9 | [Synonyms]
TLCK
TLCK HCL
TOS-LYS-CMK HCL
TLCK HYDROCHLORIDE
TOS-LYS-CHLOROMETHYLKETONE HCL
TOSYL-L-LYSYL-CHLOROMETHANE HCL
TOSYL-L-LYSINE CHLOROMETHYLKETONE HCL
N-ALPHA-TOSYL-LYS-CHLOROMETHYLKETONE HCL
NALPHA-P-TOSYL-L-LYSIN CHLOROMETYL KETONE
1-CHLORO-3-TOSYLAMIDO-7-AMINO-L-2-HEPTANONE
Chloro-3-tosylamido-7-amino-2-heptanone-HCl
1-Chloro-3-tosylamido-7-amino-2-heptanoneHCl
N-ALPHA-P-TOSYL-L-LYSIN CHLOROMETYL KETONE HCL
Nα-Tosyl-Lys Chloromethyl Ketone, Hydrochloride
L-1-CHLORO-3-TOSYLAMIDO-7-AMINO-2-HEPTANONE HCL
Tosyllysine Chloromethyl Ketone (hydrochloride)
TLCK (Tosyl-L-lysyl-chloromethane hydrochloride)
N-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
N-ALPHA-TOSYL-LYS CHLOROMETHYL KETONE, HYDROCHLORIDE
1-CHLORO-3-TOSYLAMIDO-7-AMINO-2-HEPTANONE HYDROCHLORIDE
p-N-(7-amino-1-chloro-2-oxohept-3-yl)toluenesulphonamide
N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
1-CHLORO-3-TOSYLAMIDO-7-AMINO-L-2-HEPTANONE HYDROCHLORIDE
N-ALPHA-P-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
P-TOLUENESULFONYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
1-CHLORO-3-TOSYLAMIDO-7-AMINO-2-HEPTA NONE HYDROCHLORIDE 98%
(3S)-1-CHLORO-3-TOSYLAMIDO-7-AMINO-2-HEPTANONE HYDROCHLORIDE
(3S)-7-AMINO-1-CHLORO-3-TOSYLAMINO-2-HEPTANONE HYDROCHLORIDE
L-1-CHLORO-3-(4-TOSYLAMIDO)-7-AMINO-2-HEPTANONE HYDROCHLORIDE
Nalpha-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride
Nα-Tosyl-Lys Chloromethyl Ketone, Hydrochloride - CAS 4238-41-9 - Calbiochem | [EINECS(EC#)]
224-199-0 | [Molecular Formula]
C14H22Cl2N2O3S | [MDL Number]
MFCD00065395 | [MOL File]
4238-41-9.mol | [Molecular Weight]
369.3 |
| Chemical Properties | Back Directory | [Melting point ]
~165 °C (dec.) | [storage temp. ]
2-8°C | [solubility ]
H2O: 50 mg/mL | [form ]
powder | [color ]
white to pink | [Water Solubility ]
Soluble in water | [InChI]
1S/C14H21ClN2O3S.ClH/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;/h5-8,13,17H,2-4,9-10,16H2,1H3;1H/t13-;/m0./s1 | [InChIKey]
YFCUZWYIPBUQBD-ZOWNYOTGSA-N | [SMILES]
[S](=O)(=O)(N[C@@H](CCCC[N+H3])C(=O)CCl)c1ccc(cc1)C.[Cl-] |
| Hazard Information | Back Directory | [Uses]
Inhibitor of papain and trypsin | [Biological Activity]
Cell permeable: no''EC50 = 80 μM blocking nitric oxide synthase induced by interferon-γ and lipopolysaccharides in macrophages''Primary Target
trypsin like proteases''Product does not compete with ATP.''Reversible: no | [IC 50]
Caspase-3: 12.0 μM (IC50); Caspase-7: 19.3 μM (IC50); Caspase-6: 54.5 μM (IC50) |
|
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
Merck Millipore
|
| Tel: |
1-400-889-1988 400-889-1988 |
| Website: |
http://www.merckmillipore.com |
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|